The Formulation
Targeted at the root.
ClascoteroneX is built around clascoterone — an ingredient designed to act locally on the scalp, right where hair follicles live.
The problem, in plain language
Why hair thins in the first place
The most common form of hair thinning — androgenetic alopecia — is driven largely by androgens such as DHT. In genetically sensitive follicles, DHT binds to androgen receptors and, over time, the follicle shrinks (miniaturisation). Hair grows back thinner, shorter and lighter, until some follicles stop producing visible hair.
Step 1
Healthy follicle
Thick, long strand.
Step 2
DHT binds to receptor
The follicle starts to shrink.
Step 3
Miniaturised follicle
Thin, short strand.
How clascoterone works
Blocking the signal, not the hormone
Clascoterone is an androgen-receptor inhibitor. Instead of lowering hormone levels throughout the body, it competes with DHT at the receptor in the skin — so the signal that drives follicle shrinkage is reduced locally.
After it does its job in the skin, clascoterone is broken down into an inactive compound (cortexolone). This is why it is described as acting locally, with limited systemic exposure.
Clascoterone occupies the androgen receptor so DHT can’t bind as easily.
Local by design
Oral anti-androgens act across the whole body. ClascoteroneX is applied only where it is needed: the scalp.
What the research says
A clinically studied ingredient
Established in dermatology
Clascoterone has been used in dermatology since 2020. Acne is also driven by androgens in the skin, the same signal this routine targets.
Large hair growth studies
In 2025, two large studies (SCALP 1 & SCALP 2) of a 5% clascoterone solution — 1,758 participants — reported significant improvement in target-area hair count versus placebo.
Long-term safety follow-up
12-month follow-up data published in 2026 reported a safety profile comparable to placebo.
Those trials studied a specific 5% solution. They are not studies of ClascoteroneX itself. Clascoterone is not yet FDA-approved for hair loss.
Read the full research summary in our Library →Full ingredient list
Everything inside, nothing hidden
| Ingredient | Role | Why it’s there |
|---|---|---|
| Clascoterone — 5% w/v | Active | Locally targets androgen receptors in the scalp |
| Solvent base | Vehicle | Helps the active reach the scalp and dries quickly without residue |
| Conditioning agents | Support | Keep the scalp comfortable during daily use |
Active
Clascoterone — 5% w/v
Locally targets androgen receptors in the scalp
Vehicle
Solvent base
Helps the active reach the scalp and dries quickly without residue
Support
Conditioning agents
Keep the scalp comfortable during daily use
Free from: fragrance. Non-greasy finish.
See full ingredients & warnings →Quality & manufacturing
Made with pharmaceutical discipline
Quality-controlled production
Every lot is batch-tested
Light-protective bottle with precision dropper
Lot number & expiry printed on every box
Before you start
Who it’s for — and who should not use it
Designed for
Adults noticing gradual thinning at the crown, hairline or part line; people who want a topical, local approach; people who want a simple daily routine.
Talk to a doctor first / do not use if
Pregnant, trying to conceive, or breastfeeding · under 18 · broken, irritated or sunburned scalp · known allergy to any ingredient · sudden, patchy or rapid hair loss (this may have another cause that needs diagnosis).
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Keep exploring
ClascoteroneX is a scalp-care product. Statements on this website have not been evaluated by the U.S. Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Individual results vary. Consult a healthcare professional before use, especially if you are pregnant, breastfeeding, under 18, or taking other medications.